Antibody engaging a target on the surface of a senescent cell

SenoVac immuno-senolytic technology

神诺威免疫抗衰技术

Technology

技术

Precision immune clearance begins with the right Seno-antigen.

精准免疫清除,始于正确的Seno-antigen。

We identify surface antigens that distinguish pathological senescent cells, then translate those discoveries into immune-mediated therapeutic strategies designed for selectivity, durable clearance and tissue recovery.

我们发现能够区分病理性衰老细胞的表面抗原,并将这些发现转化为兼顾选择性、持续清除能力与组织修复潜力的免疫治疗策略。

Explore the Science探索科学机制

The biological background and our solution

疾病背景与神诺威解决方案

From Senescent Cell Burden to Precision Immune Clearance

从衰老细胞累积到精准免疫清除

Senescent cells accumulate with age and disease, sustaining inflammation, fibrosis and tissue dysfunction. SenoVac identifies selective surface antigens and connects them with immune mechanisms designed to clear pathological cells while preserving healthy tissue.

衰老细胞随年龄与疾病持续累积,推动慢性炎症、纤维化与组织功能损伤。神诺威识别具有选择性的表面抗原,并将其连接至免疫清除机制,在保护健康组织的同时清除病理性衰老细胞。

01

Senescent Cell Burden Drives Chronic Tissue Damage

衰老细胞累积推动慢性组织损伤

Progression from senescent cell accumulation and fibrosis to senolysis and tissue restoration
Accumulating senescent cells amplify SASP signaling, chronic inflammation and fibrosis. Removing this burden creates an opportunity for regeneration and restoration.
衰老细胞累积会放大SASP信号、慢性炎症与纤维化。清除这一病理负担,为组织再生与功能恢复创造条件。
02

Multiple Routes to Selective Immune Clearance

多路径实现选择性免疫清除

Vaccine, CAR-T or NK, antibody-drug and SynAND-TCE strategies for clearing senescent cells
SenoVac develops complementary approaches spanning preventive vaccination, engineered immune cells, antibody-guided clearance and logic-gated T-cell engagement.
神诺威构建互补的清除路径,覆盖预防性疫苗、工程化免疫细胞、抗体引导清除与逻辑门控T细胞接合方案。

Scientific depth behind the platform

平台背后的科研积累

Science Built for Translation

面向转化的科研平台

SenoVac brings together aging biology, therapeutic-target discovery, multi-context expression evidence and AI-enabled candidate design within one connected research platform.

神诺威将衰老生物学、治疗靶点发现、多场景表达证据与AI辅助候选设计整合于同一科研平台。

This foundation connects biological mechanisms with practical development choices, supports disciplined target evaluation and advances selective immune-clearance strategies toward translation.

这一体系将生物学机制与实际研发选择相连接,支持严谨的靶点评估,并推动选择性免疫清除策略走向转化。

25+ Years of Aging Research年衰老研究积累
100+ Curated Therapeutic Targets个精选治疗靶点
31K+ Target Expression Data Repository条靶点表达数据
200K+ Candidate Drug–Target Pairs组候选药物—靶点匹配